Feeds:
Posts
Comments

Posts Tagged ‘Clinical trial’

Join the Watch Party & Learn About The GAIN Alzheimer’s Trial!

Alzheimer’s Speaks Radio – Shifting dementia care from crisis to comfort around the world one episode at a time by raising all voices and delivering sounds news, not just sound bites since 2011.

Watch Party on YouTube!

Thursday June 30th, 2020 –

2pm ET, 1pm CT, 12pm MT, 11am PT & 7pm London, 8pm South Africa and on the 26th at 5am in Australia AET

Click Below To Listen To Show

The host of Alzheimer’s Speaks Radio, Lori La Bey, will be talking with the Chief Medical Officer at Cortexyme, Dr. Michael Detke.  Cortexyme is a bio tech company that is developing therapies targeting bacteria P. gingivalis, commonly associated with gum disease, that can infect the brain and cause Alzheimer’s disease.  Dr. Detke is a board-certified psychiatrist and has been involved in clinical drug research and development for more than 20 years, having trained in psychiatry at Harvard Medical School. 

You or a loved one may be eligible for the study if you:

  • Are 55 to 80 years old
  • Have been diagnosed with mild to moderate Alzheimer’s disease
  • Have a caregiver or family member who will attend study visits, report on daily activities and oversee medication use

Learn more about the GAIN Alzheimer’s Trial and locations in your area

Support Alzheimer’s Speaks work by Downloading the Song “Clarion Call” by the Mark Arneson Band featuring Mia Dorr on your favorite msuic APP.

July 15th – Join Lori La Bey for

Artis Senior Living Memory Cafe

July 16th – Join Lori La Bey

& Artis Senior Living

July 23rd – Join Lori La Bey

& Artis Senior Living

Lori La Bey Can Help Your Organization Switch To Virtual Presentations For Staff Trainings, Family Support, Perspective Clients and Support Gatherings.

Accepting Dementia in Your Life

Watch the Video Below

For a Complete List of Dementia Chats Videos Click Here

2 FREE SERVICE OFFERS BELOW

We would love to here your thoughts and comments on this tip.

Do You Like to Sing, Humm or Dance?

See What Others Have Say About Lori La Bey

I want to echo the thanks and appreciation of my colleagues… Your presentations were movingly authentic, fully engaging and wonderfully informative. Thank you for all that you are doing, and all that you’ve done for us!

Carla Koehl, Director of Community RelationsArtis Senior Living of Lexington

 “Feedback from the conference planning committee and our leadership team was extremely positive. Many attendees commented that she was one of the best speakers they had heard.” 

Pat Sylvia, Director of Education & Member Development LeadingAge WA

For More Testimonial

                                            Diana Pierce and Lori La Bey

Downloadable Tips Below

Find A Memory Café In Your Area

Push Dementia Forward – Participate!

Gains Alzheimer's Trail - Premiere on Alzheimer's Speaks YouTube Channel

Read Full Post »

Exciting Alzheimer’s Trial Available!

Alzheimer’s Speaks Radio – Shifting dementia care from crisis to comfort around the world one episode at a time by raising all voices and delivering sounds news, not just sound bites since 2011.

Thursday June 25th, 2020 –

2pm ET, 1pm CT, 12pm MT, 11am PT & 7pm London, 8pm South Africa and on the 26th at 5am in Australia AET

Click Below To Listen To Show

Lori La Bey, the host of Alzheimer’s Speaks Radio will be talking with the Chief Medical Officer at Cortexyme, Dr. Michael Detke.  Cortexyme is a bio tech company that is developing therapies targeting bacteria P. gingivalis, commonly associated with gum disease, that can infect the brain and cause Alzheimer’s disease.  Dr. Detke is a board-certified psychiatrist and has been involved in clinical drug research and development for more than 20 years, having trained in psychiatry at Harvard Medical School. 

Learn more about the GAIN Alzheimer’s Trial and locations in your area

Support Alzheimer’s Speaks work by Downloading the Song “Clarion Call” by the Mark Arneson Band featuring Mia Dorr on your favorite msuic APP.

July 16th – Join Lori La Bey

& Artis Senior Living

Lori La Bey Can Help Your Organization Switch To Virtual Presentations For Staff Trainings, Family Support, Perspective Clients and Support Gatherings.

Accepting Dementia in Your Life

Watch the Video Below

For a Complete List of Dementia Chats Videos Click Here

2 FREE SERVICE OFFERS BELOW

We would love to here your thoughts and comments on this tip.

Do You Like to Sing, Humm or Dance?

See What Others Have Say About Lori La Bey

I want to echo the thanks and appreciation of my colleagues… Your presentations were movingly authentic, fully engaging and wonderfully informative. Thank you for all that you are doing, and all that you’ve done for us!

Carla Koehl, Director of Community RelationsArtis Senior Living of Lexington

 “Feedback from the conference planning committee and our leadership team was extremely positive. Many attendees commented that she was one of the best speakers they had heard.” 

Pat Sylvia, Director of Education & Member Development LeadingAge WA

For More Testimonial

                                            Diana Pierce and Lori La Bey

Downloadable Tips Below

Find A Memory Café In Your Area

Push Dementia Forward – Participate!

Read Full Post »

Alzheimer’s Speaks Radio talks

with Dr. Sharon Cohen, 

a dementia trial investigator.

Archives of all shows available after the first airing.

Listen to the show below

On Tuesday, September 25th, Lori La Bey host of Alzheimer’s Speaks Radio will be talking with Dr. Cohen who will speak openly on the future of trials on Alzheimer’s Disease and the quest for treatments and a cure. Learn about becoming a “Medical Hero” and how they celebrated.  The event was held on Friday, September 21st, World Alzheimer’s Day, at the Toronto Memory Program. The patients were testing BAN2401, one of the most promising drugs in the pipeline, and were given a personal readout of their results. 

Contact information about the Toronto Memory Program can be found at:

www.TorontoMemoryProgram.com

Toronto Memory Program Revised Logo_FINAL (Dec 2012)

Copy of DC_HQ_062714_banneryellow2

Today our Dementia Chats Experts, those diagnosed and living with cognitive impairment, discuss what they would like to see their communities provide them to show they are truly a “Dementia Friendly Business or Communities.”  You will find great tips for businesses and communities to consider.

Our experts today are: Michael Ellenbogen, Laurie Scherrer, Bob Savage and Truthful Loving Kindness. Lori La Bey, founder of Alzheimer’s Speaks facilitates the conversation. Lori can be reached at or visit Alzheimer’s Speaks website.

Voices of Those Diagnosed with Dementia

Dementia Chats™ was created with the intention to educate people living with dementia; their care partners both family and friends as well as professionals and advocates. Our Experts are those diagnosed with dementia. We have been doing this series since July of 2012.

For More Dementia Chats Videos 

keynote_no_text__2_pic

Looking for a Keynoter, Consultant or Trainer?

See what LeadingAge has to say about Lori La Bey

 “Feedback from the conference planning committee and our leadership team was extremely positive. Many attendees commented that she was one of the best speakers they had heard.” 

Pat Sylvia, Director of Education & Member Development LeadingAge Washington

For More Testimonials

Click Below to Download the Tips

Push Research Forward – Join the A-List

What Matters Most: Cognitive Self Assessment


Read Full Post »

Alzheimer’s Disease – Like The Heart Of An Onion

Alzheimer’s Disease – Like The Heart Of An Onion

onionBy Lori La Bey found of Alzheimer’s Speaks

This is a story I wrote about a visit with my Mother with Alzheimer’s years ago.

She is now passed and I do miss her so.

mom pic in the heart of the onionI went to visit my Mother today at Maplewood Care Center, her nursing home.  It’s hard to believe she has been there since 2001, and that she asked to move into the nursing home.  Who would have thought?  Surely not me, Mom was always going to live with us. Nine years in the nursing home has been an incredible journey of friendship, love, and awakening.    Never in my wildest dreams would I have imagined my Mother’s path would change my career and my way of life, but it did and I can’t thank her enough for what she has taught me through her illness.

mcdonalds hot fudge sundaeToday when I went to visit Mom it was just prior to supper time.  I decided to pick up a Hot Fudge Sundae from Mc Donald’s for her anyways.  She loves her Sundaes from McDonald’s chipped teeth and all.  As I scooped the ice cream with the black plastic spoon that came with the sundae, I was anticipating Mom’s smile once her lips felt the cold.  Instead, Mom’s lips popped open and closed around the spoon.  I gently pulled the spoon out from the lips that trapped it as the ice cream melted in her mouth.  My wrist soon turned to scoop another serving of hot fudge, and I saw Mom winkle her face like crisp dollar bill being scrunched in a powerful hand.   Today It was evident the cold was causing her pain, yet she wanted more.  I guess the fudge out weighted the pain, for today anyways.

After dessert was gone we went onto the main course.  Chow mien, peas and carrots, a whipped fruit salad, all per aide.  The baby food texture does nothing for my pallet, but it works well for Mom and she doesn’t seem to mine.  Who am I to complain anyways, especially when I know she can’t chew with her dilapidated teeth.  As I chatted with Mom and the staff I noticed one of my favorite people was missing from the dining room.

“Where’s  Lillian?” I asked.

“Oh she passed about two weeks ago.” One of the staff said in a soft compassionate voice.  My heart sunk to my toes.  I hadn’t seen Lillian in the past month between being out of town and visiting Mom later at night when she was in her room.  I felt horrible I hadn’t looked for Lillian when I was there.  My mind raced knowing there was no way of going back in time. I will miss Lillian, she made my heart smile.let_my_heart_smile_through_my_eyes_quoteLillian had befriended my Mother, watching and checking up on her throughout the years.  When I would come to visit Mom, Lillian would scurry over, grab my hand, look deep into my eyes, and share stories with me. Her soft loving smile positioned on her aged and wrinkled face was one of my favorite things to see.  Some days Lillian would sit and visit with Mom and me, other times she thought I was her daughter.  On these occasions she would grab my hand, lead me off to a private setting where we could sit next to each other holding hands and sharing stories uninterrupted.  Lillian’s crystal blue eyes could calm a tornado and her soft smile framed a strong and amazing woman who was a gift to know.  It was just in the last year Lillian started to fail physically losing her balance; needing a walker; which many times she would forget was hers.  Lillian was the elder, the wise one on the floor loving and caring for those around her until the day she died. If I’m not mistaken, she recently turned 104 years old.  I would have loved to have met her family, but it’s not likely now.  I will miss her beautiful crystal blues eyes, her soft fail hands that would reach for mine, and her compassionate voice like that of an angel.

Losing Lillian has made me realize, Mom could go any time.  Mentally, I’ve known this, but the loss of Lillian made the thought sink into every pour of my being.  One day, there may be no reason to go to the nursing home.  Mom will not be waiting for me.  She will not surprise me with subtle facial expressions, or a goofy comment, or a little giggle that lightens my spirit.  What in the world will I do when the time comes for Mom to pass?

I know many think I should be relieved as I am released from this “Caregiver Role.”  They view this journey I’ve been on with my Mother as a burden.  But truth be told, I will deeply miss her.  I will miss that shell of a body that is all many people see.  For me there is so much more to Mom than her shell.  I guess I see Alzheimer’s disease like peeling an onion.  There are many layers and like the heart of the onion the soul of a person is always in the middle and never dies first.

For More Information on Dementia and Caregiving Click Below.

alz_spks_programs_graphic_w_HNP_082115Join an Alzheimer’s disease Clinical Trial Today. Click Below.

New home page blog banner 10327_Banner_L_475x358 090215No Insurance is Needed to Participate.

Join the Global Effort To Raise Awareness of Dementia. Click Below.

PA-Join-Us R

Read Full Post »

From XETV San Diego 6

By Candice Nguyen February 11, 2013

 

A new drug is being tested at UCSD‘s Department of Neuroscience to help early onset Alzheimer’s patients. Doctors are studying the medication‘s ability to slow down memory loss. It’s part of research being conducted around the world called The Scarlet Road Study (www.scarletroadstudy.com).

Dr. Michael Rafii is one of the researchers.  He says, “The drugs are being used at an earlier stage where the patient is not dependent on anyone else. They would remain in the independent stage.” He adds, “What we really need to do is stop the progression of the disease before it reaches the dementia stage.”

Currently, six patients are being treated with this medication at UCSD. The school serves as one of the largest sites in the world. Subjects receive an injection once a month, MRI’s every couple of months, spinal taps and memory tests. The drug works to remove an abnormal protein in the brain called beta amyloid, which is known to cause memory loss.

70-year-old Pat Donnelly is one of the subjects. About four years ago, his wife Missy started noticing he would forget little things like leaving cabinet doors open. Then an incident at an airport luggage carousel alarmed her.

“Instead of letting it go around again and picking it up later, he continued holding it and was plowing into people almost knocking them over,” she described. A trip to the doctor’s office confirmed Pat had early stage Alzheimer’s Disease.  Missy worked with Dr. Rafii to get her husband into the clinical trial.

Pat has been part of the two-year study for just over a year now. However, he and his doctors are “blinded” meaning they don’t know if he is receiving a placebo or medication. Pat and Missy say they understand a cure for Alzheimer’s or a medication to slow down memory loss may not be discovered in their lifetimes, bu they are taking part in this groundbreaking research to hopefully help future patients.

If you think you may be eligible for the study, call 858-246-1300.

Read Full Post »

By Kevin Woo, Special to Alzheimer’s Speaks | December 12, 2012

Last year a drug known as AC253, which was intended to help diabetics, was pulled from clinical trials and never made it to market. But medical researchers at the University of Alberta have discovered that the same drug, AC253, could block the toxic effects of amyloid protein that lead to brain cell death.

Drs. Jack Jhamandas and Ryoichi Kimura tested the memory of animals with normal brain cells against those with Alzheimer’s.  When the animals with Alzheimer’s were given AC253 and the memory tests were repeated, the memory of those with Alzheimer’s was restored to levels close to those with normal brain cells.

Dr. Jhamandas told Science Daily, “This is very important because it tells us that drugs like this might be able to restore memory, even after Alzheimer’s disease may have set in.”

Amyloid protein is found in exceedingly high amounts in the  memory and cognition parts of the brains of patient’s with Alzheimer’s and diminishes memory.

For AC253 to effective, however, pharmaceutical companies will need to find a way for the drug to penetrate brain cells more easily.

“I think what we discovered may be part of the solution but i can’t say it will be the solution,” added Jhamandas in his interview with Science Daily. “There is a long list of drugs and approaches that haven’t panned out as expected in the fight against Alzheimer’s.  I don’t think one drug or approach will solve Alzheimer’s disease because it’s a complicated disease but I am cautiously optimistic about our discovery and its implications.”

Read Full Post »

By Kevin Woo, Special to Alzheimer’s Speaks | December 5, 2012

 

The United Kingdom’s Telegraph newspaper reported this morning that in early 2013 a small number of Alzheimer’s patients with mild-to-moderate stage symptoms could get access to a drug currently known as MK-8931.

The drug is in clinical trial but if proven effective millions of people world-wide could benefit. The study will involve 1,700 Alzheimer’s patients world-wide.  Half will be given MK-8931 and the other half a placebo.

In early testing the drug has proven to be effective at halting amyloid cascade, the buildup of structures between cells, which causes Alzheimer’s Disease.

Dr. Richard Perry, a consultant neurologist and lecturer at Imperial College Healthcare NHS Trust, told the Telegraph in an interview, “The idea of this drug is to stop the production of abnormal levels of beta amyloid in the brain. It’s about getting in early, so that if less amyloid is produced, less plaques will come together. From what I have seen of the phase one trial results, this drug looks encouraging in terms of reducing the level of abnormal beta-amyloid in spinal fluid.”

Researchers say the results won’t be final until 2016.

The Telegraph story can be read in its entirety here:  http://bit.ly/TESaKk

Read Full Post »

Another Way To Fund Alzheimer’s Research

By Carole Larkin

Pfizer is the pharmaceutical company that makes Aricept, what was the most prescribed drug for Alzheimer’s disease.  Aricept went generic over a year ago. Pfizer also was the pharmaceutical company behind Dimebon; a promising Alzheimer’s drug that made it through phase II clinical trials, but was ultimately abandoned as “not effective”. Research continues on Alzheimer’s drugs at Pfizer and at other drug companies today.

I came across an article in the January- February article of the AARP.org/bulletin written by Patricia Barry that caught my interest.  Permit me to quote a few lines from the article.

“Drug market analysts have long speculated on how Pfizer might try and maintain profits after Lipitor- the anticholesterol prescription drug that has earned up to $12 billion annually over 15 years-lost patent protection on Nov. 30. Now they know.

Pfizer has launched an unprecedented campaign to persuade patients to stay with its brand instead of switching to the newer lower-cost generic, atorvastatin. In a controversial move, Pfizer has made deals to stop many insurance plans from covering the generic. Instead the plans will cover only Lipitor and charge patients lower copays- which sounds like a great deal for many consumers.

But for people with Medicare D plans especially, there’s a catch. If a part D plan decides to cover Lipitor but not the generic, enrollee’s will hit the gap (donut hole) faster because only the higher brand price will count towards the limit ($2930 in 2012). Such arrangements will continue until May 31, when more drug makers will be able to market generic versions of Lipitor and competition will cut back prices dramatically. Meanwhile, other blockbuster drugs are due to come off patent in 2012, and experts think that their makers will likely copy Pfizer’s strategy.

Pfizer’s move brought a swift response from the Senate’s Finance committee and Special committee on Aging, which have asked the company for details of its deals with the benefit management companies that serve as middlemen between drugmakers and insurers.”

What if the committees mandate that this strategy can go forward for all prescriptions that come off patent in 2012, only if the profits gained go towards research on Alzheimer’s drugs?

What do you think?

 

Carole Larkin

Carole B. Larkin is the Geriatric Care Manager for ThirdAge Services, specializing in all forms dementia care. She has a Master of Applied Gerontology degree with a specialty in Aging Services from the University of North Texas.  Carole is a certified specialist in “Best Care” practices by both the Alzheimer’s Foundation of America and the National Council of Certified Dementia Specialists  and has worked for the Dallas Chapter of the Alzheimer’s Association.

   Carole is a Certified Alzheimer’s Educator and trains home care companies, assisted living communities, memory care communities and nursing homes in dementia care techniques to enable a higher quality of life for persons with dementia and their families.  She has training in mediation skills and works with eldercare attorneys resolving difficult family issues regarding dementia.   

Carole functions as the hub of the wheel of resources available to help families, and makes specific recommendations of the highest quality resources available at every price point, saving time and money for the families who secure her services.

She is a member of the National Association of

, the American Society on Aging,  the Dallas Area Gerontological Society, OWL, the Friends of the Alzheimer’s Disease Center at UT Southwestern Medical Center  and Sigma Chi Omega, the national Gerontology Academic Honor and Professional Society.  She has been a Care Manager for more than seven years and has served older adults and their families for over two decades.

214-649-1392

Email Carole

www.thirdageservices.com

Read Full Post »

%d bloggers like this: